Need to make the 2 columns as read only in matrix table.

Just find the class and add a class as .prop('disabled',true);
Like, jQuery('input[type="text"]').eq(5).prop('disabled',true);

https://community.qualtrics.com/XMcommunity/discussion/comment/55109#Comment_55109This is the code I used to disable the first row last column cell.
jQuery('#'+this.questionId+' tbody tr:first td:last').find('input[type="text"]').attr('readonly','readonly')  
Kindly update me with the similar code to disable the last cells in each columns.

Hi jbk ,
you can achieve the same assuming structure remains same using below code which shoul be added into Qualtrics API :
Qualtrics.SurveyEngine.addOnload(function()
{
/*Place your JavaScript here to run when the page loads*/

});

Qualtrics.SurveyEngine.addOnReady(function()
{
/*Place your JavaScript here to run when the page is fully displayed*/
let text=document.querySelectorAll("input[type=text]")
for(let i=0;i{  

  text[1].readOnly=true;
  text[text.length-1].readOnly=true;
   
   
}
});

Qualtrics.SurveyEngine.addOnUnload(function()
{
/*Place your JavaScript here to run when the page is unloaded*/

});

Hope it resolves your query😊!!

jbk Here is the solution,
jQuery('#'+this.questionId+' tbody tr:last td:last').find('input[type="text"]').attr('readonly','readonly') 
Alternatively, you can use eq instead and get the required textbox (going from left to right to downwards from 0) to set to readonly function.